Formulating for cats: taurine, arginine and vitamin A

Cats are obligate carnivores with nutrient needs that dogs do not share. Getting them wrong has caused serious disease in the past. The essentials every cat formula must get right.

PNL
Guires PNL InsightsWritten by the nutrition science and regulatory teams
Reviewed byGuires PNL scientific team
Published24 Sep 2026
Last checked24 Sep 2026
Reading time7 minutes
Key takeaways
  • Cats need dietary taurine; deficiency was linked to heart failure in cats in 1987.
  • AAFCO cat minimums for taurine are 0.10% DM for dry and 0.20% DM for canned foods.
  • Cats need preformed vitamin A, dietary arachidonic acid and more niacin than dogs.
  • Propylene glycol is prohibited in US cat food; cats respond strongly to umami.
EvidenceStrongRated by the Guires Pet Nutrition Lab scientific team

01Taurine: the lesson from 1987

In 1987, researchers linked low plasma taurine to dilated cardiomyopathy in cats, and showed it was reversible with taurine supplementation 1. The finding changed commercial cat food worldwide. Today, AAFCO sets cat minimums of 0.10% taurine on a dry-matter basis for extruded foods and 0.20% for canned foods — higher for canned because processing and gut bacteria increase losses 2.

02What makes cats different

NutrientWhy cats are differentWhat we do
ArginineCats cannot make enough; a meal lacking arginine can cause serious illnessProtein sources and levels checked for every recipe
Vitamin ACats cannot convert β-carotene to vitamin APreformed vitamin A added and verified
Arachidonic acidCats cannot make enough from linoleic acidAnimal fat sources included
NiacinCats convert little tryptophan to niacinHigher niacin supply in the premix
ProteinHigher requirement; protein is also used for energyRecipes built to the cat profile 2

These differences are summarised in the NRC nutrient requirements of dogs and cats 3.

03Ingredients to avoid or limit

Propylene glycol, used as a humectant in some semi-moist dog products, is prohibited in cat food in the US 4. Preservatives such as benzoic acid need particular care in cat formulas.

04Designing for feline taste

Cats lack a working sweet receptor and are strongly drawn to umami. Research suggests the appeal of tuna comes partly from inosine monophosphate and free L-histidine, which together enhance umami taste 5. Cats also eat many small meals, so palatability studies are designed around their feeding pattern 6.

Cat formulation checklist

  • Formulate to the cat nutrient profile from the start.
  • Verify taurine and vitamin A in the finished product.
  • Allow for processing losses in canned foods.
  • Exclude propylene glycol from cat products.
  • Test acceptance with a cat panel.
Guires Pet Nutrition Lab verdict

Cats have non-negotiable requirements. Formulate from the feline profile, verify by analysis and test with cats.

05Questions brands ask

Why is the taurine minimum higher for canned food?

Heat processing and gut bacteria increase taurine losses in canned diets, so AAFCO sets 0.20% DM for canned vs 0.10% DM for dry.

Can a dog treat be given to cats?

Not safely by default: ingredients such as propylene glycol are prohibited in US cat food.

Sources

  1. Pion PD et al. (1987). Myocardial failure in cats associated with low plasma taurine. Science. Source ↗
  2. AAFCO dog and cat food nutrient profiles. Source ↗
  3. National Research Council (2006). Nutrient Requirements of Dogs and Cats. Source ↗
  4. 21 CFR 589.1001 — Propylene glycol in or on cat food. Source ↗
  5. McGrane SJ et al. (2023). Umami taste perception and preferences of the domestic cat. Chem Senses. Source ↗
  6. Watson P et al. (2023). Animals. Source ↗

Evidence reviewed by the Guires Pet Nutrition Lab scientific team. This article is general information for product developers and is not legal or veterinary advice.

How to cite this article

Choose your referencing style, then copy. Check your university’s, journal’s or regulator’s guide for local variations.

Guires Pet Nutrition Lab. (2026, September 24). Formulating for cats: taurine, arginine and vitamin A. Guires Pet Nutrition Lab Insights. https://www.petnutritionlab.com/insights/formulating-for-cats

This article summarises published evidence for product developers. Cite the original sources above for specific findings, and do not reproduce this article as your own work.

Developing a cat product?

We formulate from feline requirements and test with cat panels.

FEDIAFAAFCO

Every Guires PNL product is formulated to comply with the FEDIAF Nutritional Guidelines and the AAFCO Dog and Cat Food Nutrient Profiles. Neither body issues certificates to manufacturers, so compliance is verified independently against their published standards — and every product comes with a complete documentation package for regulatory submissions in the EU, US, Australia and Asian markets.

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