Nutritional and functional claims reviewed for each market and backed by published research, analysis or studies — so every claim on the pack can be defended.
Regulatory work is planned with formulation from the start, so the product, the label and the claims are cleared together.
Nutritional, functional or medical — and what that means in each market.
Claims phrased within what the evidence and the law support.
Peer-reviewed research, dose and product data compiled for each claim.
Active levels in the finished product checked against the evidence.
Palatability, digestibility, in vitro or feeding studies where evidence is missing.
Website, social and sales materials checked for consistent claims.
Some actives have strong trial evidence; others have little or none.
Positive studies are more likely to be published than negative ones.
Disease claims can move a product into veterinary-medicine rules.
A claim is only valid if the finished product delivers the studied dose.
Every claim collected.
Claim type per market.
Research and data compiled.
Missing evidence identified.
Studies designed if needed.
Final wording agreed.
Peer-reviewed findings that shape how we design and interpret this work.
A 2022 meta-analysis of 72 trials found clear evidence for omega-3s in canine and feline osteoarthritis, but “a very marked non-effect” for chondroitin–glucosamine.
Evidence reviews come first, so studies target ingredients and doses that can work.
Probiotic trials in dogs and cats reporting an effect were far more likely to be published (5 of 7) than those that did not (1 of 5).
We encourage reporting every result, positive or negative.
Veterinary trials with pharmaceutical funding reported positive outcomes 56.9% of the time, against 29.1% with no funding stated.
Funding is disclosed and outcomes are pre-specified, so sponsored research stays credible.
Each application has its own page with the evidence, the actives and the claim boundaries we work within.
Firm stools, comfortable digestion and a balanced gut microbiome.
Keeping active and ageing pets moving comfortably.
A healthy skin barrier and a glossy coat, driven by the right balance of omega-6 and omega-3 fatty acids, protein quality and key micronutrients.
Nutrition that supports calm behaviour during stressful moments.
Every ingredient we choose for claims support & substantiation is assessed for nutrient contribution, digestibility, processing behaviour, palatability and the rules in your market — and sourced to your specification.
Regulation updates, the latest research, recalls and market trends that shape pet food claims — written by our formulation, testing and regulatory teams.
Pet foods and most supplements should use nutritional or functional claims; disease claims can make the product a veterinary medicine.
Peer-reviewed research at the dose your product delivers, supported by analysis and, where needed, product studies.
Yes — palatability and feeding studies with partner panels, digestibility, in vitro screening and contract research.
Tell us your product, your question and your market — our scientists will come back with a study design and next steps.
Every Guires PNL product is formulated to comply with the FEDIAF Nutritional Guidelines and the AAFCO Dog and Cat Food Nutrient Profiles. Neither body issues certificates to manufacturers, so compliance is verified independently against their published standards — and every product comes with a complete documentation package for regulatory submissions in the EU, US, Australia and Asian markets.
How we verify compliance →