Evidence varies by ingredient
A meta-analysis of 72 trials found clear evidence for omega-3s in canine and feline osteoarthritis, but a very marked non-effect for chondroitin–glucosamine.
We rank actives by evidence strength before setting doses.
Delivery formats matched to the active ingredient, the species and how owners actually dose — with attention to stability, acceptance and claim boundaries.
A supplement only works if the active survives manufacture and storage, and if the pet accepts every dose. The format, carrier, palatant system and packaging decide both.
We develop soft chews, powders, oils, tablets, pastes and probiotic formats with dose per serving set from the evidence, stability tracked through shelf life and claims reviewed for your market.
Start your project with Guires PNLEvery format starts from the species, the life stage and the nutritional objective.
The most popular dog format, with active stability and palatability designed together.
Easy dosing on food, with flow, mixing and stability control.
Omega-3 oils and liquid actives with oxidation control.
Precise dosing for potent actives and veterinary channels.
Palatable pastes for cats and fussy dogs.
Strain survival through processing and shelf life, supported by our bioscience lab.
Vitamins, probiotics, omega-3s and botanicals degrade with heat, moisture and oxygen; overages and packaging protect them.
Bitter or strong actives need palatant and texture work so pets take every dose.
The active level per chew or scoop must match the evidence, by body weight.
Supplement claims differ by market; wording is reviewed against the rules in each.
Active, species, format, dose and market.
Dose per serving, carrier and palatant system.
Bench batches for acceptance and handling.
Active levels tracked through shelf life.
Wording checked for your market.
Specification and process sheet.
Peer-reviewed findings that shape how we develop this format.
A meta-analysis of 72 trials found clear evidence for omega-3s in canine and feline osteoarthritis, but a very marked non-effect for chondroitin–glucosamine.
We rank actives by evidence strength before setting doses.
A systematic review of 17 dog studies found only a very limited effect of probiotics in acute gut disease.
Probiotic claims are matched to what the evidence supports.
In a 56-day placebo-controlled trial in 34 cats, alpha-casozepine significantly improved fear and anxiety-related behaviour.
Actives and doses come from controlled trials in the target species.
Each application has its own page with the evidence, the actives and the claim boundaries we work within.
Keeping active and ageing pets moving comfortably.
Nutrition that supports calm behaviour during stressful moments.
Firm stools, comfortable digestion and a balanced gut microbiome.
Helping pets stay healthy for longer.
Every ingredient we choose for pet supplements is assessed for nutrient contribution, digestibility, processing behaviour, palatability and the rules in your market — and sourced to your specification.
Regulation updates, the latest research, recalls and market trends that shape pet supplements — written by our formulation, testing and regulatory teams.
Every project at Guires Pet Nutrition Lab runs inside an ISO 9001:2015 certified quality system and FSSAI-licensed operations, with documented methods, calibrated instruments, traceable raw materials and reviewed reports — so the results behind your product can be checked and defended.
It depends on the active, the species and how owners dose; soft chews suit most dog products, while pastes and powders often suit cats.
Yes. Our Pet Bioscience Lab tests strain identity and live counts through processing and shelf life.
Yes. We review claims against the rules for your market; final compliance rests with the brand owner placing the product on the market.
Real client projects — the problem, the science and the result.
Tell us the species, the format and the market — we will come back with an approach and next steps.
Every Guires PNL product is formulated to comply with the FEDIAF Nutritional Guidelines and the AAFCO Dog and Cat Food Nutrient Profiles. Neither body issues certificates to manufacturers, so compliance is verified independently against their published standards — and every product comes with a complete documentation package for regulatory submissions in the EU, US, Australia and Asian markets.
How we verify compliance →